Hai-Qiang Mai Selected Research

Nasopharyngeal Carcinoma

12/2023	Phase I dose-escalation study of nab-paclitaxel combined with cisplatin and capecitabin as induction chemotherapy followed by concurrent chemoradiotherapy in patients with nasopharyngeal carcinoma.
11/2023	Toripalimab Plus Chemotherapy for Recurrent or Metastatic Nasopharyngeal Carcinoma: The JUPITER-02 Randomized Clinical Trial.
11/2023	Radiomic signatures reveal multiscale intratumor heterogeneity associated with tissue tolerance and survival in re-irradiated nasopharyngeal carcinoma: a multicenter study.
11/2023	Reduced-dose radiotherapy for Epstein-Barr virus DNA selected staged III nasopharyngeal carcinoma: A single-arm, phase 2 trial.
11/2023	Eosinophil dynamics during chemo-radiotherapy correlate to clinical outcome in stage Ⅱ-Ⅳa nasopharyngeal carcinoma patients: Results from a large cohort study.
11/2023	Paclitaxel liposome, cisplatin and 5-fluorouracil-based induction chemotherapy followed by de-escalated intensity-modulated radiotherapy with concurrent cisplatin in stage IVA-IVB childhood nasopharyngeal carcinoma in endemic area: a phase II, single-arm trial.
10/2023	Enhancer remodeling activates NOTCH3 signaling to confer chemoresistance in advanced nasopharyngeal carcinoma.
5/2023	Nasopharyngeal necrosis contributes to overall survival in nasopharyngeal carcinoma without distant metastasis: a comprehensive nomogram model.
1/2023	Clinical characteristics and prognostic factors affecting survival after radical radiotherapy for early and late post-treatment metastatic nasopharyngeal carcinoma.
1/2023	Camrelizumab combined with apatinib in patients with first-line platinum-resistant or PD-1 inhibitor resistant recurrent/metastatic nasopharyngeal carcinoma: a single-arm, phase 2 trial.

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Hai-Qiang Mai Research Topics

Disease

186	Nasopharyngeal Carcinoma 12/2023 - 02/2002
59	Neoplasm Metastasis (Metastasis) 05/2023 - 02/2005
53	Neoplasms (Cancer) 11/2023 - 04/2004
6	Necrosis 11/2023 - 10/2013
5	Carcinoma (Carcinomatosis) 01/2023 - 06/2015
3	Disease Progression 11/2023 - 11/2015
3	Mucositis 01/2023 - 08/2017
3	Neutropenia 01/2023 - 09/2013
3	Xerostomia 01/2020 - 05/2005
2	Radiation Injuries (Radiation Sickness) 11/2023 - 07/2008
2	Hearing Loss (Hearing Impairment) 01/2023 - 01/2020
2	Head and Neck Neoplasms (Head and Neck Cancer) 01/2023 - 10/2019
2	Infections 01/2023 - 01/2015
2	Leukopenia 01/2023 - 12/2018
2	Carcinogenesis 01/2022 - 11/2015
2	Anemia 10/2021 - 01/2015
2	Thrombocytopenia (Thrombopenia) 10/2021 - 01/2018
2	Body Weight (Weight, Body) 09/2021 - 11/2019
2	Nasopharyngeal Neoplasms (Cancer of the Nasopharynx) 01/2021 - 01/2021
2	Bites and Stings (Sting) 07/2020 - 11/2019
2	Hypoxia (Hypoxemia) 01/2020 - 04/2006
2	Stomatitis 10/2019 - 09/2013
2	Pain (Aches) 10/2019 - 10/2019
2	Osteoradionecrosis 01/2017 - 09/2006
2	Nasopharyngitis 12/2015 - 12/2004
2	Lymphatic Metastasis 10/2015 - 10/2006
1	Tertiary Lymphoid Structures 01/2023
1	Brain Injuries (Brain Injury) 01/2023
1	Brain Edema (Cerebral Edema) 01/2023
1	Septic Shock (Toxic Shock Syndrome) 01/2023
1	COVID-19 12/2022
1	Fatty Liver 01/2022
1	Prostatic Neoplasms (Prostate Cancer) 01/2022

Drug/Important Bio-Agent (IBA)

46	DNA (Deoxyribonucleic Acid)IBA 11/2023 - 04/2013
25	Cisplatin (Platino)FDA LinkGeneric 12/2023 - 02/2005
11	Biomarkers (Surrogate Marker)IBA 11/2023 - 01/2015
9	Proteins (Proteins, Gene)FDA Link 11/2019 - 10/2006
7	Capecitabine (Xeloda)FDA Link 12/2023 - 04/2004
6	Fluorouracil (Carac)FDA LinkGeneric 01/2023 - 04/2004
6	3-nitrophenyl 3-piperidinecarboxylate (MNPC)IBA 11/2022 - 01/2016
5	Gemcitabine FDA Link 11/2023 - 01/2020
5	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 10/2022 - 08/2013
5	Indicators and Reagents (Reagents)IBA 01/2017 - 06/2011
4	Hemoglobins (Hemoglobin)IBA 09/2021 - 06/2005
4	Endothelin A ReceptorIBA 08/2013 - 05/2005
3	Docetaxel (Taxotere)FDA Link 12/2023 - 12/2018
3	toripalimabIBA 11/2023 - 01/2021
3	Paclitaxel (Taxol)FDA LinkGeneric 11/2023 - 12/2018
3	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 01/2023 - 09/2015
3	LigandsIBA 01/2023 - 06/2005
3	ChemokinesIBA 01/2023 - 01/2019
3	Immune Checkpoint InhibitorsIBA 01/2023 - 10/2019
3	AlbuminsIBA 01/2023 - 11/2019
3	Messenger RNA (mRNA)IBA 01/2021 - 10/2006
3	Cetuximab (Erbitux)FDA Link 01/2019 - 08/2017
3	Viral DNAIBA 01/2019 - 11/2015
3	C-Reactive ProteinIBA 07/2018 - 01/2015
2	apatinibIBA 01/2023 - 01/2023
2	PlatinumIBA 01/2023 - 01/2023
2	nedaplatinIBA 12/2021 - 01/2018
2	EnzymesIBA 10/2021 - 02/2016
2	Interleukin-6 (Interleukin 6)IBA 07/2020 - 07/2017
2	CytokinesIBA 07/2020 - 11/2019
2	nitazoxanide (NTZ)FDA Link 01/2019 - 01/2018
2	nimotuzumabIBA 01/2019 - 01/2018
2	Membrane Proteins (Integral Membrane Proteins)IBA 07/2017 - 02/2002
2	Lipoproteins (Lipoprotein)IBA 07/2016 - 08/2014
2	Carboplatin (JM8)FDA LinkGeneric 09/2015 - 10/2012
2	Chemokine ReceptorsIBA 08/2013 - 06/2005
2	EndostatinsIBA 05/2013 - 11/2007
2	Endothelin-1 (Endothelin 1)IBA 04/2011 - 04/2006
1	Albumin-Bound Paclitaxel FDA Link 12/2023
1	130-nm albumin-bound paclitaxelIBA 12/2023
1	Liposomes (Liposome)IBA 11/2023
1	camrelizumabIBA 01/2023
1	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 01/2023
1	Tyrosine Kinase InhibitorsIBA 01/2023
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2023
1	Bevacizumab (Avastin)FDA Link 01/2023
1	Histone DemethylasesIBA 01/2023
1	AerosolsIBA 12/2022
1	VaccinesIBA 12/2022
1	AndrogensIBA 01/2022
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2022
1	Androgen Receptors (Androgen Receptor)IBA 01/2022

Therapy/Procedure

69	Radiotherapy 11/2023 - 04/2004
45	Chemoradiotherapy 12/2023 - 10/2009
45	Drug Therapy (Chemotherapy) 11/2023 - 08/2006
35	Induction Chemotherapy 12/2023 - 02/2005
24	Intensity-Modulated Radiotherapy (Radiotherapy, Intensity Modulated) 11/2023 - 12/2012
18	Therapeutics 11/2023 - 07/2008
6	Adjuvant Chemotherapy 01/2023 - 02/2017
6	Neoadjuvant Therapy 01/2019 - 09/2013
5	Immunotherapy 01/2023 - 02/2015
5	Re-Irradiation 01/2020 - 07/2008
4	Aftercare (After-Treatment) 01/2023 - 11/2007
4	Neck Dissection (Radical Neck Dissection) 11/2022 - 01/2018
1	Contraindications 01/2023
1	Personal Protective Equipment 12/2022
1	TP protocol 01/2022